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Blood Gas Analysis of Respiratory Depression during Sevoflurane Inhalation Induction for General Anesthesia in the Disabled Patients

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À±Å¿Ϡ( Yoon Tae-Wan ) - ´Ü±¹´ëÇб³ Ä¡°ú´ëÇÐ ¼Ò¾ÆÄ¡°úÇб³½Ç
±è¼º¿À ( Kim Seung-Oh ) - ´Ü±¹´ëÇб³ Ä¡°ú´ëÇÐ ¼Ò¾ÆÄ¡°úÇб³½Ç

Abstract

¼¼º¸Ç÷ç¶õ¿¡ ÀÇÇÑ ÀÏȸ ȯ±â·®Àº ³·Àº ¿ë·®¿¡¼­´Â È£Èí¼öÀÇ Áõ°¡·Î ¾ÈÁ¤ÀûÀÌ´Ù. ±×·¯³ª ÁøÁ¤ ±íÀÌ°¡ Áõ°¡Çϸé ÆóÆ÷ ȯ±â´Â ¼¼º¸Ç÷ç¶õ¿¡ ÀÇÇØ °¨¼ÒµÇ¾î °á°úÀûÀ¸·Î´Â PaCO2°¡ Áõ°¡ÇÑ´Ù. È£Èí ¾ïÁ¦ÀÇ ¹ß»ýÀº ±íÀÌ ÁøÁ¤µÈ Àå¾Ö ȯÀÚ¿¡¼­ ½ÉÇÑ Àú»ê¼ÒÁõ°ú °íź»êÇ÷ÁõÀÇ À§ÇèÀ» Áõ°¡½ÃŲ´Ù. ¼¼º¸Ç÷ç¶õ ÈíÀÔ ¸¶Ãë´Â ¿©·¯ À§Ç輺ÀÌ ³»Á¦µÇ¾î ÀÖÀ¸¸ç ü³» »ê ¿°±â »óÅ¿¡ µû¶ó Ç÷¿ªÇÐÀû º¯È­°¡ ¹ß»ýÇϱ⿡ ¿¹±âÄ¡ ¸øÇÑ ¹®Á¦ »óȲÀÌ ¹ß»ýÇÒ ¼ö ÀÖ´Ù. ¼¼º¸Ç÷ç¶õÀ¸·Î Àå¾ÖÀÎÀÇ ¸¶Ãë À¯µµ ½Ã ¹ß»ýÇϴ ȣÈí ¾ïÁ¦·Î ÀÎÇÑ Ã¼³» »ê ¿°±â »óÅ°¡¾ÈÁ¤ÇÑÁö ¾Ë¾Æº¸°íÀÚ ÀÌ ¿¬±¸¸¦ ÁøÇàÇÏ¿´´Ù. ¸¶Ãë À¯µµ´Â 4 vol% ¼¼º¸Ç÷ç¶õ, 4 L/min ¾Æ»êÈ­Áú¼Ò, 4 L/min »ê¼Ò¸¦ ÀÚ¹ß È£Èí ÇÏ¿¡¼­È¯ÀÚ ¾È¸éºÎ¿¡ ¸¶½ºÅ©¸¦ °ÅÄ¡ÇÏ¿© À¯µµÇÏ¿´´Ù. ±× µÚ ȯÀÚÀÇ ÀÇ½Ä¼Ò½Ç ¹× ±ÙÀ° ±äÀå ¿ÏÈ­ ÈÄ Áï½Ã Àü¹®°¡¿¡ ÀÇÇØ IV lineÀ» °ÅÄ¡ÇÑ µÚÁ¤¸Æ äÇ÷À» ÇÏ¿© Á¤¸Æ ³» Ç÷¾×°¡½º ºÐ¼®À» ÇÏ¿´´Ù. ±íÀº ÁøÁ¤ »óÅ¿¡¼­ Àüü ȯÀÚÀÇ Æò±Õ pH´Â 7.36 ¡¾ 0.06À¸·Î ÃøÁ¤µÇ¾ú´Ù. PvCO2´ÂÀüü ȯÀÚ¿¡¼­´Â Æò±Õ 48.8 ¡¾ 8.50 mmHg·Î ÃøÁ¤µÇ¾ú´Ù. HCO3?´Â Àüü ȯÀÚ¿¡¼­ Æò±Õ 27.2 ¡¾ 3.0 mmol/L·Î ÃøÁ¤µÇ¾ú´Ù. °á·ÐÀûÀ¸·ÎÀå¾ÖÀÎÀ» ´ë»óÀ¸·Î ÇÑ Ä¡°ú Áø·á½Ã ¼¼º¸Ç÷ç¶õÀ» ÀÌ¿ëÇÑ ÈíÀÔ ÁøÁ¤¿¡ ´ëÇÑ Ã¼³» »ê ¿°±â ¹ÝÀÀÀº ºñ±³Àû ¾ÈÁ¤ÀûÀ̾ú´Ù.

Tidal volume by sevoflurane in small amounts is stable due to the increase in the breathing rate. But alveolus ventilation decreases due to sevoflurane as the degree of sedation increases; this ultimately causes PaCO2 to rise. The occurrence of suppression of breath increases the risk of severe hypoxia and hypercapnia in deeply sedated patients with disabilities. Sevoflurane inhalation anesthesia has a number of risks and may have unexpected problems with hemodynamic changes depending on the underlying state of the body. This study was conducted to examine the stability of internal acid-base system caused by respiratory depression occurring when patients with disabilities are induced by sevoflurane. Anesthetic induction was carried out by placing a mask on top of the patient¡¯s face and through voluntary breathing with 4 vol% of sevoflurane, 4 L/min of nitrous oxide, and 4 L/min of oxygen. After the patient¡¯s loss of consciousness and muscle relaxation, IV line was inserted by an expert and intravenous blood gas was analyzed by extracting blood from vein. In a deeply sedated state, the average amount of pH of the entire patients was measured as 7.36 ¡¾ 0.06. The average amount of PvCO2 of the entire patients was measured as 48.8 ¡¾ 8.50 mmHg. The average amount of HCO3 - of the entire patients was measured as 27.2 ¡¾ 3.0 mmol/L. In conclusion, in dental treatment of patients with disabilities, the internal acid base response to inhalation sedation using sevoflurane is relatively stable.

Å°¿öµå

Patient with disabilities; Sevoflurane inhalation sedation; General anesthesia; Respiratory depression

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